ea0056oc8.3 | MicroRNAs as biomarkers in endocrine diseases | ECE2018
van Kralingen J.C.
, Larsen C.K.
, Connell J.M.
, Freel E.M.
, Zennaro M.C.
, MacKenzie S.M.
, Davies E.
Introduction: MicroRNA (miRNA) has been shown to post-transcriptionally regulate physiological systems modulating blood pressure, including the adrenal biosynthesis of aldosterone. This raises the possibility that levels of specific miRNAs circulating in plasma might reflect these functional effects and have diagnostic value in the identification of hypertension and its various underlying causes. In a previous study, we measured plasma levels of miRNAs originating from the miR...